I were just playing Fist of Mars for a change when I noticed that the plot seemed somewhat distorted and unnormal. So I decided to look around...
I found out that if you let Mars Angels defeat more mosqitoes than you, the game will be quite different in the future than it would be otherwise. This affects not only plot, but also the gameplay. I still haven't finished yet, so I don't know how radical the cchanges are, but... they seem to be pretty darn radical so far.
If anything this is at least a good reason to replay the game.
Regards,
Caldera