Necrobump here, but I've heard from a little birdy that there may be a chance of a ZOE 3 in the future... though it's still rumors.
Still... CyGames has managed to salvage ZOE2 from the trainwreck that was the """HD""" Collection by Konami!
They're really big fans of it, which is why they redid the HD port in the first place
♥Fingers crossed CyGames gets ahold of the ZOE IP...